

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–7) and one of the most widely referenced neuropeptides in cognitive and neurobiology research. This high-purity sequence offers unparalleled stability and molecular integrity. Researchers investigating neural signaling pathways, BDNF upregulation, neuroprotection, and synaptic plasticity mechanisms will find this compound essential. Each batch is synthesized using automated SPPS and purified by HPLC. The resulting lyophilized powder demonstrates exceptional solubility and reconstitution consistency. This compound is intended strictly for in-vitro and laboratory research use.
Semax is a research-grade nootropic peptide derived from the ACTH 4–7 Pro-Gly-Pro extension, valued for its stability against enzymatic degradation. Unlike its parent ACTH fragment, Semax is engineered for extended bioavailability in in-vitro models. Researchers studying neural signaling, brain-derived neurotrophic factor (BDNF) modulation, and neuroprotection consistently rely on its batch-to-batch uniformity.
Semax's primary research applications center on central nervous system signaling, BDNF pathway modulation, neuroprotection, and cognitive neurophysiology. As a synthetic ACTH analog, Semax is studied for its capacity to interact with melanocortin receptors and influence downstream neurotrophin cascades, including the upregulation of BDNF in neuronal cell models. It is also a widely used comparator in studies contrasting neuropeptides such as Selank.
Our peptides are synthesized using SPPS to yield an ultra-pure final product. Subsequent purification by preparative HPLC eliminates truncated sequences and deletion impurities. Final verification is achieved through ESI-MS, confirming the exact molecular mass. We guarantee 99%+ purity, documented in a batch-specific COA.
This product is strictly for research and laboratory use only. It is not approved by the FDA or any global regulatory body for human consumption, veterinary use, or therapeutic application. The purchaser assumes all responsibility for the proper handling, storage, and application of this compound. It must only be handled by qualified professionals in a controlled laboratory setting. By purchasing this product, you agree to abide by all local and international laws regarding the use of research chemicals.

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Find answers to common questions regarding storage, reconstitution, and testing guidelines for this specific compound.